Mako Shark (Deep Blue Sea)

The Mako Sharks are the main antagonists of the 1999 science fiction horror film, Deep Blue Sea. They were genetically engineered to harvest protein complex for a cure for Alzheimer's, but they were later shown to be more intelligent and dangerous than spoken. Even while they still instinctive and regular sea predators, these sharks were obviously savage, resentful, and vituperative toward Aquatica scientists for their experiment on them. As stated from Russell and Carter's conversation regarding what Mako Sharks wanted much later in the film, it is revealed that all this time, the sharks also missed their freedom, but too helpless with their current state prior to given gene therapy.

Once given therapy gene on their brains that enhanced their intelligence, this ultimately enhanced Mako Shark's awareness about their surroundings and became more resourceful than ever. The largest shark revealing its enhanced awareness by chop off Jim's arm when the latter lower his guard. One of the sharks even thrown a stretcher on the underwater window's glass so water would flood the whole facility as it aware that the cannot stalk on humans without water to breathe with their gills. Given that they were chooses to killed all humans first before flee to the open sea, they believed that they won't free as long as the humans in Aquatica still alive. Unfortunately, this also led to their downfall.