Neuron appeared in 1997 video game called Yoshi's Story. Neurons are a species featured in Yoshi's Story. They appear to be large multi-colored worm-like creatures with whiskers on the top of their heads. They only appear in one level, 4-4: Neuron Jungle. The Yoshis can mostly use their heads as platforms to reach other places, but at times Neurons can push Yoshis off the edges of platforms to their defeat. Certain Neurons will also be nestled in inconvenient areas, blocking places and fruits off with their tall bodies. They have a spiked, underwater counterpart called the Sea Cactus.